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A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation

机译：估计与基因座数目成线性比例的连锁不平衡图形模型的方法和程序，及其在基因下降模拟中的应用

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Motivation: Efficient models for genetic linkage disequilibrium (LD) are needed to enable appropriate statistical analysis of the dense, genome-wide single nucleotide polymorphism assays currently available.

机译：动机：需要有效的遗传连锁不平衡（LD）模型，以对目前可用的全基因组单核苷酸多态性分析进行适当的统计分析。

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Thomas, Alun;
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年度 2009
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正文语种 en
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专利

1. A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation [J] . Thomas A Bioinformatics . 2009,第10期

机译：估计与基因座数目成线性比例的连锁不平衡图形模型的方法和程序，及其在基因下降模拟中的应用
2. A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation [J] . Alun Thomas Bioinformatics . 2009,第10期

机译：估计与基因座数目成线性比例的连锁不平衡图形模型的方法和程序，及其在基因下降模拟中的应用
3. Estimation of graphical models whose conditional independence graphs are interval graphs and its application to modelling linkage disequilibrium [J] . Thomas A Computational statistics & data analysis . 2009,第5期

机译：条件独立图为区间图的图形模型的估计及其在连锁不平衡建模中的应用
4. Comparison of Different Methods for Handling Linkage Disequilibrium in Genetic-Association Analyses via Simulation [C] . Wang Yongke, Wang Wenhui, Luan Yihui International Conference on Biomedical Engineering and Informatics;BMEI '09 . 2009

机译：遗传关联分析中处理连锁不平衡的不同方法的仿真比较
5. Analysis of linkage disequilibrium and haplotype at the single -minded homology 2 locus in four populations, as a model for analysis of candidate loci in complex genetic disease. [D] . Carlson, Christopher Scott. 2000

机译：分析四个群体中一心一意的同源性2位点的连锁不平衡和单倍型，作为分析复杂遗传病中候选基因座的模型。
6. A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci and their application to gene drop simulation [O] . Alun Thomas -1

机译：估计与基因座数目成线性比例的连锁不平衡图形模型的方法和程序及其在基因下降模拟中的应用
7. Genetic Analysis Workshop 15: simulation of a complex genetic model for rheumatoid arthritis in nuclear families including a dense SNP map with linkage disequilibrium between marker loci and trait loci [O] . 2007

机译：遗传分析研讨会15：模拟核心家庭中类风湿关节炎的复杂遗传模型，包括密集的SNP图以及标记基因座和性状基因座之间的连锁不平衡

A method and program for estimating graphical models for linkage disequilibrium that scale linearly with the number of loci, and their application to gene drop simulation

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